P2X3 antagonist 38

Modify Date: 2025-08-26 11:52:20

P2X3 antagonist 38 structure	Common Name	P2X3 antagonist 38
	CAS Number	2545974-71-6	Molecular Weight	478.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₂₅F₃N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of P2X3 antagonist 38

P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].

Name	P2X3 antagonist 38

Description	P2X3 antagonist 38 (compound 4) is a potent and orally active P2X3 antagonist with IC50 values of 0.132, 0.165, 0.421 µM for hP2X3, rP2X3, gpP2X3, respectively[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor
Target	P2X3 Receptor:0.132 μM (IC50)
References	[1]. YunFeng Chen, et al. N-carboxamidopyrazoline derivative serving as p2x3 receptor antagonist and applications. WO2022028154A1.

Molecular Formula	C₂₂H₂₅F₃N₆O₃
Molecular Weight	478.47

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