2924403-17-6

2924403-17-6 structure

Name: PD-1/PD-L1-IN-34
Chemical Name: PD-1/PD-L1-IN-34
CAS Number: 2924403-17-6
Molecular Formula: C₃₅H₃₃ClN₂O₃
Molecular Weight: 565.10
Catalog: Signaling Pathways Immunology/Inflammation PD-1/PD-L1
Create Date: 2023-11-11 18:50:08
Modify Date: 2024-01-09 13:33:23
PD-1/PD-L1-IN-30 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-30 inhibits tumor growth by activating the immune microenvironment[1].

Name	PD-1/PD-L1-IN-34

Description	PD-1/PD-L1-IN-30 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-30 inhibits tumor growth by activating the immune microenvironment[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1 Research Areas >> Inflammation/Immunology
References	[1]. Jing T, et al. Discovery and Optimization of Novel Biphenyl Derivatives Bearing Cyclopropyl Linkage as Potent Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Inhibitors. J Med Chem. 2023 May 25;66(10):6811-6835.

Molecular Formula	C₃₅H₃₃ClN₂O₃
Molecular Weight	565.10