PD-1/PD-L1-IN-34

Modify Date: 2024-01-09 13:33:23

PD-1/PD-L1-IN-34 Structure
PD-1/PD-L1-IN-34 structure
Common Name PD-1/PD-L1-IN-34
CAS Number 2924403-17-6 Molecular Weight 565.10
Density N/A Boiling Point N/A
Molecular Formula C35H33ClN2O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PD-1/PD-L1-IN-34


PD-1/PD-L1-IN-30 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-30 inhibits tumor growth by activating the immune microenvironment[1].

 Names

Name PD-1/PD-L1-IN-34

 PD-1/PD-L1-IN-34 Biological Activity

Description PD-1/PD-L1-IN-30 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-30 inhibits tumor growth by activating the immune microenvironment[1].
Related Catalog
References

[1]. Jing T, et al. Discovery and Optimization of Novel Biphenyl Derivatives Bearing Cyclopropyl Linkage as Potent Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Inhibitors. J Med Chem. 2023 May 25;66(10):6811-6835.  

 Chemical & Physical Properties

Molecular Formula C35H33ClN2O3
Molecular Weight 565.10
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