Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Skp2 inhibitor 1
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Skp2 inhibitor 1
Price: ￥1500.0/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2760612-63-1

2760612-63-1 structure

2760612-63-1 structure

Name: Skp2 inhibitor 1
Chemical Name: Skp2 inhibitor 1
CAS Number: 2760612-63-1
Molecular Formula: C₂₃H₂₃ClN₄O
Molecular Weight: 406.91
Catalog: Signaling Pathways Metabolic Enzyme/Protease E1/E2/E3 Enzyme
Create Date: 2023-11-17 21:01:16
Modify Date: 2024-01-05 10:37:05
Skp2 inhibitor 1 (compound 14i) is a potent and selective Skp2 inhibitor against the Skp2-Cks1 interaction with an IC50 of 2.8 μM. Skp inhibitor 1 exhibits anticancer activity[1].

Name	Skp2 inhibitor 1

Description	Skp2 inhibitor 1 (compound 14i) is a potent and selective Skp2 inhibitor against the Skp2-Cks1 interaction with an IC50 of 2.8 μM. Skp inhibitor 1 exhibits anticancer activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> E1/E2/E3 Enzyme
Target	Growth arrest-specific protein 6(Gas6)-Cell Cyclin Kinase Subunit 1(Cks1) [1]IC50：2.8 μM(Growth arrest-specific protein 6,Gas6; Cell Cyclin Kinase Subunit 1,Cks1)[1]
References	[1]. Zhang K, et al. Discovery of Novel 1,3-Diphenylpyrazine Derivatives as Potent S-Phase Kinase-Associated Protein 2 (Skp2) Inhibitors for the Treatment of Cancer. J Med Chem. 2023 Jun 8;66(11):7221-7242.

Molecular Formula	C₂₃H₂₃ClN₄O
Molecular Weight	406.91

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