371919-80-1

371919-80-1 structure

371919-80-1 structure

Name: STAT6-IN-3
Chemical Name: STAT6-IN-3
CAS Number: 371919-80-1
Molecular Formula: C₃₂H₃₅IN₃O₇P
Molecular Weight: 731.51
Catalog: Signaling Pathways JAK/STAT Signaling STAT
Create Date: 2023-09-28 17:24:45
Modify Date: 2024-01-12 22:20:53
STAT6-IN-3 (Compound 18a) is a STAT6 inhibitor (IC50= 44 nM). STAT6-IN-3 targets the Src Homology 2 (SH2) domain of STAT6. STAT6-IN-3 can be used for research of inflammation such as asthma[1].

Name	STAT6-IN-3

Description	STAT6-IN-3 (Compound 18a) is a STAT6 inhibitor (IC50= 44 nM). STAT6-IN-3 targets the Src Homology 2 (SH2) domain of STAT6. STAT6-IN-3 can be used for research of inflammation such as asthma[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Signaling Pathways >> JAK/STAT Signaling >> STAT Research Areas >> Inflammation/Immunology
References	[1]. Mandal PK, et al. Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. J Med Chem. 2015 Nov 25;58(22):8970-84.

Molecular Formula	C₃₂H₃₅IN₃O₇P
Molecular Weight	731.51