255713-53-2

255713-53-2 structure

Name: A-123189
Chemical Name: A-123189
CAS Number: 255713-53-2
Molecular Formula: C₂₆H₂₈N₄O₃S
Molecular Weight: 476.59
Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
Create Date: 2023-11-27 15:24:08
Modify Date: 2024-01-27 22:02:20
A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].

Name	A-123189
Synonyms	A 123189 A123189

Description	A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
References	[1]. K P Briski, et al. Antagonism of type II, but not type I glucocorticoid receptors results in elevated basal luteinizing hormone release in male rats. Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 9, 7 May 2001, Pages 1119-1121.