A-123189

Modify Date: 2024-01-27 22:02:20

A-123189 structure	Common Name	A-123189
	CAS Number	255713-53-2	Molecular Weight	476.59
	Density	1.261±0.06 g/cm3(Predicted)	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₈N₄O₃S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of A-123189

A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].

Name	A-123189
Synonym	More Synonyms

Description	A-123189 is a selective and potent α1D antagonist with Kis of 0.312 and 0.17 for human α1D and rat α1D, respectively. A-123189 displays selectivities between 10- to 20-fold for the α1D receptor over the human α1A and rat α1A receptors[1].
Related Catalog	Research Areas >> Endocrinology Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
References	[1]. K P Briski, et al. Antagonism of type II, but not type I glucocorticoid receptors results in elevated basal luteinizing hormone release in male rats. Bioorganic & Medicinal Chemistry Letters, Volume 11, Issue 9, 7 May 2001, Pages 1119-1121.

Density	1.261±0.06 g/cm3(Predicted)
Molecular Formula	C₂₆H₂₈N₄O₃S
Molecular Weight	476.59

A 123189

A123189

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A-123189

Use of A-123189

Names

A-123189 Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.