2868357-11-1
2868357-11-1 structure
- Name: Glucocorticoid receptor modulator 1
- Chemical Name: Glucocorticoid receptor modulator 1
- CAS Number: 2868357-11-1
- Molecular Formula: C24H23ClN2O4S
- Molecular Weight: 470.97
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Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC 50 value of 9 nM and 130 nM for NF-κB and AP-1 , respectively. Glucocorticoid receptor modulator 1 can effectively reduce the expression of inflammatory factors IL-6 , IL-1β, TNF-α, also can relieve dermatitis in mice [1] .
| Name | Glucocorticoid receptor modulator 1 |
|---|
| Description | Glucocorticoid receptor modulator 1 is a highly potent and orally active non-steroidal selective glucocorticoid receptor modulator with an IC 50 value of 9 nM and 130 nM for NF-κB and AP-1 , respectively. Glucocorticoid receptor modulator 1 can effectively reduce the expression of inflammatory factors IL-6 , IL-1β, TNF-α, also can relieve dermatitis in mice [1] . |
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| Molecular Formula | C24H23ClN2O4S |
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| Molecular Weight | 470.97 |