2662908-25-8
2662908-25-8 structure
- Name: Glucocorticoid receptor-IN-1
- Chemical Name: Glucocorticoid receptor-IN-1
- CAS Number: 2662908-25-8
- Molecular Formula: C24H19F4N7O2
- Molecular Weight: 513.45
- Catalog: Signaling Pathways GPCR/G Protein Glucocorticoid Receptor
- Create Date: 2022-08-14 22:24:01
- Modify Date: 2024-01-09 16:42:36
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Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1].
| Name | Glucocorticoid receptor-IN-1 |
|---|
| Description | Glucocorticoid receptor-IN-1 (Compound WX002) is a selective glucocorticoid receptor (GR) modulator with anti-inflammatory effect. Glucocorticoid receptor-IN-1 exhibits very good transcriptional repressive activity with an IC50 of 2.11 nM against hMMP1, and transcriptional activation activity with an EC50 of 5.59 nM against MMTV[1]. |
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| Related Catalog | |
| In Vitro | Glucocorticoid receptor-IN-1 (Compound WX002) shows inhibitory effect on CYP3A4 with an IC50 of 16.7 µM[1]. |
| References |
[1]. Guoli Zhang, et al. Benzo[d][1,2,3]triazole ether compound. WO2021136431. |
| Molecular Formula | C24H19F4N7O2 |
|---|---|
| Molecular Weight | 513.45 |