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Product Name: (R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID
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4350-07-6

4350-07-6 structure

4350-07-6 structure

Name: (R)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPANOIC ACID
Chemical Name: 5-hydroxy-D-tryptophan
CAS Number: 4350-07-6
Molecular Formula: C₁₁H₁₂N₂O₃
Molecular Weight: 220.22500
Catalog: Research Areas Neurological Disease
Create Date: 2018-09-05 21:05:03
Modify Date: 2024-01-06 13:44:23
D-5-Hydroxytryptophan (D-5-HTP) is the D-isomers of 5-HTP, and can be isolated from DL-5-hydroxytryptophan by successive separations[1].

Name	5-hydroxy-D-tryptophan
Synonyms	(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid Tryptophan,5-hydroxy-,D D-5-HTP (D-2-Amino-3-(5-hydroxyindolyl)propionic acid C11H12N2O3 5-Hydroxytryptophan D-form HRP D-Tryptophan,5-hydroxy D-5-Hydroxytryptophan

Description	D-5-Hydroxytryptophan (D-5-HTP) is the D-isomers of 5-HTP, and can be isolated from DL-5-hydroxytryptophan by successive separations[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. J Arendt, et al. Alternative pathways of 5-hydroxyindole metabolism. II. The role transamination in the metabolism of D-5-hydroxytryptophan in the rat. Biochem Pharmacol. 1967 Mar;16(3):419-22.

Melting Point	27ºC
Molecular Formula	C₁₁H₁₂N₂O₃
Molecular Weight	220.22500
Exact Mass	220.08500
PSA	99.34000
LogP	1.52820

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YN7050000

CHEMICAL NAME :: Tryptophan, 5-hydroxy-, D-

CAS REGISTRY NUMBER :: 4350-07-6

LAST UPDATED :: 199109

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C11-H12-N2-O3

MOLECULAR WEIGHT :: 220.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 69,523,1973

Hazard Codes	Xn,Xi
Risk Phrases	20/21-20/21/22-36/37/38-65
Safety Phrases	26-36
HS Code	2933990090

3017-26-3 structure

3017-26-3

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4350-07-6 structure

4350-07-6

Literature: Journal of Organic Chemistry, , vol. 22, p. 306,307

Precursor 1
3017-26-3
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%