1461658-58-1

1461658-58-1 structure

Name: CK2-IN-9
Chemical Name: CK2-IN-9
CAS Number: 1461658-58-1
Molecular Formula: C₂₃H₂₉N₉O
Molecular Weight: 447.54
Catalog: Signaling Pathways Cell Cycle/DNA Damage Casein Kinase
Create Date: 2023-12-03 11:22:13
Modify Date: 2024-01-28 13:32:29
CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat[1].

Name	CK2-IN-9

Description	CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Stem Cell/Wnt >> Wnt Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase
References	[1]. Dowling JE, et al. Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo. ACS Med Chem Lett. 2016 Jan 20;7(3):300-5.

Molecular Formula	C₂₃H₂₉N₉O
Molecular Weight	447.54