CK2-IN-9

Modify Date: 2024-01-28 13:32:29

CK2-IN-9 Structure
CK2-IN-9 structure
Common Name CK2-IN-9
CAS Number 1461658-58-1 Molecular Weight 447.54
Density N/A Boiling Point N/A
Molecular Formula C23H29N9O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CK2-IN-9


CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat[1].

 Names

Name CK2-IN-9

 CK2-IN-9 Biological Activity

Description CK2-IN-9 is a potent and selective inhibitor of CK2 kinase with an IC50 of 3 nM. CK2-IN-9 reduces Wnt reporter activity with an IC50 of 75 nM. CK2-IN-9 has low exposure (AUC=0.36 μM/h) and high clearance (CL=65 mL/min/kg) properties in rat[1].
Related Catalog
References

[1]. Dowling JE, et al. Potent and Selective CK2 Kinase Inhibitors with Effects on Wnt Pathway Signaling in Vivo. ACS Med Chem Lett. 2016 Jan 20;7(3):300-5.  

 Chemical & Physical Properties

Molecular Formula C23H29N9O
Molecular Weight 447.54