2648450-42-2
2648450-42-2 structure
- Name: GNE-7883
- Chemical Name: GNE-7883
- CAS Number: 2648450-42-2
- Molecular Formula: C28H29FN6O2
- Molecular Weight: 500.57
- Catalog: Signaling Pathways Stem Cell/Wnt YAP
- Create Date: 2023-10-26 17:48:56
- Modify Date: 2024-01-02 12:07:15
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GNE-7883 is a pan-TEAD inhibitor with anti-cell proliferation activity. GNE-7883 overcomes resistance to KRAS G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation. GNE-7883 may be used in the study of YAP/TAZ-dependent cancers[1].
| Name | GNE-7883 |
|---|
| Description | GNE-7883 is a pan-TEAD inhibitor with anti-cell proliferation activity. GNE-7883 overcomes resistance to KRAS G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation. GNE-7883 may be used in the study of YAP/TAZ-dependent cancers[1]. |
|---|---|
| Related Catalog | |
| Target |
TEAD[1]. |
| References |
| Molecular Formula | C28H29FN6O2 |
|---|---|
| Molecular Weight | 500.57 |