Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GPX4-IN-5
Price: Check
Purity: 99.58%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

2922824-09-5

2922824-09-5 structure

2922824-09-5 structure

Name: GPX4-IN-5
Chemical Name: GPX4-IN-5
CAS Number: 2922824-09-5
Molecular Formula: C₁₈H₁₇ClFNO₅
Molecular Weight: 381.78
Catalog: Signaling Pathways Apoptosis Ferroptosis
Create Date: 2024-04-09 14:54:39
Modify Date: 2024-04-09 14:54:39
GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].

Name	GPX4-IN-5

Description	GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
Target	IC50: 0.12 μM (GPX4)[1]
References	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

Molecular Formula	C₁₈H₁₇ClFNO₅
Molecular Weight	381.78

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.