GPX4-IN-5

Modify Date: 2024-04-09 14:54:39

GPX4-IN-5 structure	Common Name	GPX4-IN-5
	CAS Number	2922824-09-5	Molecular Weight	381.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₇ClFNO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GPX4-IN-5

GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].

Name	GPX4-IN-5

Description	GPX4-IN-5 (Compound C18) is a GPX4 covalent inhibitor with an IC50 value of 0.12 μM. GPX4-IN-5 (Compound C18) can induce ferroptosis for the research of triple-negative breast cancer (TNBC) [1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Apoptosis >> Ferroptosis
Target	IC50: 0.12 μM (GPX4)[1]
References	[1]. Chen T, et al. Discovery of Novel Potent Covalent Glutathione Peroxidase 4 Inhibitors as Highly Selective Ferroptosis Inducers for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2023 Jul 27;66(14):10036-10059.

Molecular Formula	C₁₈H₁₇ClFNO₅
Molecular Weight	381.78

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: GPX4-IN-5
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Purity: 99.58%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.