2944459-43-0

2944459-43-0 structure

Name: HDAC-IN-59
Chemical Name: HDAC-IN-59
CAS Number: 2944459-43-0
Molecular Formula: C₂₀H₂₅NO₇
Molecular Weight: 391.42
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2023-10-25 17:15:23
Modify Date: 2024-01-29 10:59:35
HDAC-IN-59 (compound 13a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-59 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].

Name	HDAC-IN-59

Description	HDAC-IN-59 (compound 13a) is a potent histone deacetylase (HDAC) inhibitor. HDAC-IN-59 can promote the intracellular generation of ROS, cause DNA damage, block the cell cycle at G2/M phase, and activate the mitochondria-related apoptotic pathway to induce cell apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> HDAC Signaling Pathways >> Epigenetics >> HDAC
References	[1]. Yang Y, et, al. Design, Synthesis, and Biological Evaluation of Histone Deacetylase Inhibitors Derived from Erianin and Its Derivatives. ChemMedChem. 2023 Jul 3;18(13):e202300108.

Molecular Formula	C₂₀H₂₅NO₇
Molecular Weight	391.42