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2570251-68-0

2570251-68-0 structure
2570251-68-0 structure
  • Name: HJM-561
  • Chemical Name: HJM-561
  • CAS Number: 2570251-68-0
  • Molecular Formula: C45H51ClN9O5P
  • Molecular Weight: 864.37
  • Catalog: Signaling Pathways PROTAC PROTAC
  • Create Date: 2024-09-02 17:39:57
  • Modify Date: 2025-08-25 12:23:42
  • HJM-561 is a potent, selective, orally bioavailable EGFR PROTAC. HJM-561 overcomes osimertinib (HY-15772)-resistant EGFR triple mutations and has anti-tumor activity[1].

Name HJM-561
Description HJM-561 is a potent, selective, orally bioavailable EGFR PROTAC. HJM-561 overcomes osimertinib (HY-15772)-resistant EGFR triple mutations and has anti-tumor activity[1].
Related Catalog
References

[1]. Du Y, et al. HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations. Mol Cancer Ther. 2022 Jul 5;21(7):1060-1066.  

Molecular Formula C45H51ClN9O5P
Molecular Weight 864.37
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