HJM-561

Modify Date: 2025-08-25 12:23:42

HJM-561 Structure
HJM-561 structure
Common Name HJM-561
CAS Number 2570251-68-0 Molecular Weight 864.37
Density N/A Boiling Point N/A
Molecular Formula C45H51ClN9O5P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HJM-561


HJM-561 is a potent, selective, orally bioavailable EGFR PROTAC. HJM-561 overcomes osimertinib (HY-15772)-resistant EGFR triple mutations and has anti-tumor activity[1].

 Names

Name HJM-561

 HJM-561 Biological Activity

Description HJM-561 is a potent, selective, orally bioavailable EGFR PROTAC. HJM-561 overcomes osimertinib (HY-15772)-resistant EGFR triple mutations and has anti-tumor activity[1].
Related Catalog
References

[1]. Du Y, et al. HJM-561, a Potent, Selective, and Orally Bioavailable EGFR PROTAC that Overcomes Osimertinib-Resistant EGFR Triple Mutations. Mol Cancer Ther. 2022 Jul 5;21(7):1060-1066.  

 Chemical & Physical Properties

Molecular Formula C45H51ClN9O5P
Molecular Weight 864.37
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