928023-21-6

928023-21-6 structure

Name: PPARδ agonist 9
Chemical Name: PPARδ agonist 9
CAS Number: 928023-21-6
Molecular Formula: C₂₆H₂₈ClF₃N₄O₃S
Molecular Weight: 569.04
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2024-09-29 14:55:10
Modify Date: 2025-08-26 16:36:08
PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].

Name	PPARδ agonist 9

Description	PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR Research Areas >> Metabolic Disease
Target	EC50:3.6 nM (PPARδ)[1]
References	[1]. Kato T, et al. Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure. J Med Chem. 2023 Aug 24;66(16):11428-11446..

Molecular Formula	C₂₆H₂₈ClF₃N₄O₃S
Molecular Weight	569.04