PPARδ agonist 9

Modify Date: 2025-08-26 16:36:08

PPARδ agonist 9 Structure
PPARδ agonist 9 structure
Common Name PPARδ agonist 9
CAS Number 928023-21-6 Molecular Weight 569.04
Density N/A Boiling Point N/A
Molecular Formula C26H28ClF3N4O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PPARδ agonist 9


PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].

 Names

Name PPARδ agonist 9

 PPARδ agonist 9 Biological Activity

Description PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%)[1].
Related Catalog
Target

EC50:3.6 nM (PPARδ)[1]

References

[1]. Kato T, et al. Design, Synthesis, and Anti-Inflammatory Evaluation of a Novel PPARδ Agonist with a 4-(1-Pyrrolidinyl)piperidine Structure. J Med Chem. 2023 Aug 24;66(16):11428-11446..  

 Chemical & Physical Properties

Molecular Formula C26H28ClF3N4O3S
Molecular Weight 569.04
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