Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TNG462
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: TNG462
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2760483-96-1

2760483-96-1 structure

2760483-96-1 structure

Name: TNG-462
Chemical Name: TNG-462
CAS Number: 2760483-96-1
Molecular Formula: C₂₈H₃₆N₆O₂S
Molecular Weight: 520.69
Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
Create Date: 2024-04-09 11:51:38
Modify Date: 2025-08-25 08:07:59
TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor for investigation of MTAP-deficient and/or MTA-accumulating cancers[1].

Name	TNG-462

Description	TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor for investigation of MTAP-deficient and/or MTA-accumulating cancers[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Methyltransferase
Target	PRMT5[1].
References	[1]. Kevin M Cottrell, et al. Piperidin-1- yl-n-pyrydi ne-3-yl-2-oxoacet am ide derivatives useful for the treatment of mtap-deficient and/or mt a-accumulating cancers. Patent WO2022026892A1.

Molecular Formula	C₂₈H₃₆N₆O₂S
Molecular Weight	520.69

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