TNG-462

Modify Date: 2025-08-25 08:07:59

TNG-462 Structure
TNG-462 structure
Common Name TNG-462
CAS Number 2760483-96-1 Molecular Weight 520.69
Density N/A Boiling Point N/A
Molecular Formula C28H36N6O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TNG-462


TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor for investigation of MTAP-deficient and/or MTA-accumulating cancers[1].

 Names

Name TNG-462

 TNG-462 Biological Activity

Description TNG-462 (Compound 1143) is an orally active PRMT5 inhibitor for investigation of MTAP-deficient and/or MTA-accumulating cancers[1].
Related Catalog
Target

PRMT5[1].

References

[1]. Kevin M Cottrell, et al. Piperidin-1- yl-n-pyrydi ne-3-yl-2-oxoacet am ide derivatives useful for the treatment of mtap-deficient and/or mt a-accumulating cancers. Patent WO2022026892A1.

 Chemical & Physical Properties

Molecular Formula C28H36N6O2S
Molecular Weight 520.69
InChIKey DHAGMIPSRSPWSH-GAJHUEQPSA-N
SMILES CCc1cc(NC(=O)C(=O)N2CC(C)CCC2c2ccc3sc(C4CCN(C)CC4)nc3c2)cnc1N
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.