Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ABBV-467
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: ABBV-467
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

2287186-66-5

2287186-66-5 structure

2287186-66-5 structure

Name: ABBV-467
Chemical Name: ABBV-467
CAS Number: 2287186-66-5
Molecular Formula: C₅₃H₅₁Cl₂FN₆O₉S
Molecular Weight: 1037.98
Catalog: Signaling Pathways Apoptosis Bcl-2 Family
Create Date: 2024-03-18 16:46:04
Modify Date: 2024-03-18 16:46:04
ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].

Name	ABBV-467

Description	ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	MCL-1[1].
References	[1]. Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond). 2023 Oct 25;3(1):154.

Molecular Formula	C₅₃H₅₁Cl₂FN₆O₉S
Molecular Weight	1037.98

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