ABBV-467

Modify Date: 2025-08-25 12:56:47

ABBV-467 Structure
ABBV-467 structure
Common Name ABBV-467
CAS Number 2287186-66-5 Molecular Weight 1037.98
Density N/A Boiling Point N/A
Molecular Formula C53H51Cl2FN6O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ABBV-467


ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].

 Names

Name ABBV-467

 ABBV-467 Biological Activity

Description ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM). ABBV-467 induces apoptosis. ABBV-467 induces cancer cell death and inhibits tumor growth in models of hematological malignancies, such as multiple myeloma[1].
Related Catalog
Target

MCL-1[1].

References

[1]. Yuda J, et al. Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients. Commun Med (Lond). 2023 Oct 25;3(1):154.  

 Chemical & Physical Properties

Molecular Formula C53H51Cl2FN6O9S
Molecular Weight 1037.98
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