2091887-74-8

2091887-74-8 structure

Name: ALP/Carbonic anhydrase-IN-1
Chemical Name: ALP/Carbonic anhydrase-IN-1
CAS Number: 2091887-74-8
Molecular Formula: C₁₅H₁₆N₂
Molecular Weight: 224.30
Catalog: Signaling Pathways Metabolic Enzyme/Protease Carbonic Anhydrase
Create Date: 2023-12-21 16:23:49
Modify Date: 2024-01-02 07:05:34
ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].

Name	ALP/Carbonic anhydrase-IN-1

Description	ALP/Carbonic anhydrase-IN-1 (Compound 1e) is a dual carbonic anhydrase (CA) and alkaline phosphatase (ALP) inhibitor. ALP/Carbonic anhydrase-IN-1 shows IC50 values of 0.44 µM, 1.61 µM, 0.51 µM, and 0.107 µM for CA-II, CA-IX, CA-XII, and ALP, respectively[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphatase Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase
Target	CA Ⅱ:0.44 μM (IC50) CA Ⅸ:1.61 μM (IC50) CA XII:0.51 μM (IC50) Alkaline phosphatase:0.107 μM (IC50)
References	[1]. Salman Alrokayan, et al. [1, 8]-Naphthyridine derivatives as dual inhibitor of alkaline phosphatase and carbonic anhydrase. BMC Chem. 2023 Oct 25;17(1):142.

Molecular Formula	C₁₅H₁₆N₂
Molecular Weight	224.30