2232156-31-7

2232156-31-7 structure

Name: Apoptin-derived peptide
Chemical Name: Apoptin-derived peptide
CAS Number: 2232156-31-7
Molecular Formula: C₂₂₃H₄₁₇N₈₉O₅₀S
Molecular Weight: 5177.33
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-01-08 16:11:47
Modify Date: 2025-09-12 11:56:43
Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer[1].

Name	Apoptin-derived peptide

Description	Apoptin-derived peptide is an antitumor polypeptide with cytotoxicity. Apoptin-derived peptide promotes apoptosis and necrosis of gastric cancer (GC) cells by regulating PI3K/AKT/ARNT signaling. Apoptin-derived peptide inhibited the invasion and migration of cancer cells, and inhibited the expression and phosphorylation of the subunit p85 of PI3K, which further inhibited the PI3K/AKT pathway involved in the development of gastric cancer[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> PI3K/Akt/mTOR >> Akt
References	[1]. Zhou D, et al. Apoptin-derived peptide reverses cisplatin resistance in gastric cancer through the PI3K-AKT signaling pathway [J]. Cancer Medicine, 2018, 7(4): 1369-1383.

Molecular Formula	C₂₂₃H₄₁₇N₈₉O₅₀S
Molecular Weight	5177.33