1808258-99-2

1808258-99-2 structure

Name: BMS-986172
Chemical Name: BMS-986172
CAS Number: 1808258-99-2
Molecular Formula: C₂₄H₂₂F₇N₇O₃
Molecular Weight: 589.47
Catalog: Research Areas Metabolic Disease
Create Date: 2024-02-03 19:06:14
Modify Date: 2024-02-03 19:06:14
BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1].

Name	BMS-986172

Description	BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Wei Meng, et al. Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders. J Med Chem. 2023 Sep 28;66(18):13135-13147.

Molecular Formula	C₂₄H₂₂F₇N₇O₃
Molecular Weight	589.47