BMS-986172

Modify Date: 2024-02-03 19:06:14

BMS-986172 structure	Common Name	BMS-986172
	CAS Number	1808258-99-2	Molecular Weight	589.47
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₂F₇N₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BMS-986172

BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1].

Name	BMS-986172

Description	BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Wei Meng, et al. Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders. J Med Chem. 2023 Sep 28;66(18):13135-13147.

Molecular Formula	C₂₄H₂₂F₇N₇O₃
Molecular Weight	589.47

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BMS-986172

Use of BMS-986172

Names

BMS-986172 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.