1226822-98-5

1226822-98-5 structure

Name: Cobitolimod
Chemical Name: Cobitolimod
CAS Number: 1226822-98-5
Molecular Formula: C₁₈₅H₂₃₃N₇₃O₁₀₆P₁₈S₆
Molecular Weight: 5925.20
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2024-02-04 11:30:52
Modify Date: 2025-08-24 22:49:06
Cobitolimod is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod suppresses Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway[1].

Name	Cobitolimod

Description	Cobitolimod is a DNA oligonucleotide agonist of TLR-9 with anti-inflammatory activity. Cobitolimod suppresses Th17 cells and induces anti-inflammatory FoxP3 and IL-10 expression, inhibiting the IL-17 signaling pathway[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
Target	TLR-9[1]
References	[1]. Schmitt H, Ulmschneider J, Billmeier U, Vieth M, Scarozza P, Sonnewald S, Reid S, Atreya I, Rath T, Zundler S, Langheinrich M, Schüttler J, Hartmann A, Winkler T, Admyre C, Knittel T, Dieterich Johansson C, Zargari A, Neurath MF, Atreya R. The TLR9 Agonist Cobitolimod Induces IL10-Producing Wound Healing Macrophages and Regulatory T Cells in Ulcerative Colitis. J Crohns Colitis. 2020 May 21;14(4):508-524.

Molecular Formula	C₁₈₅H₂₃₃N₇₃O₁₀₆P₁₈S₆
Molecular Weight	5925.20