1404380-58-0

1404380-58-0 structure

1404380-58-0 structure

Name: JTE-151
Chemical Name: JTE-151
CAS Number: 1404380-58-0
Molecular Formula: C₂₈H₃₇ClN₂O₄
Molecular Weight: 501.06
Catalog: Signaling Pathways Metabolic Enzyme/Protease ROR
Create Date: 2024-01-12 20:13:10
Modify Date: 2024-01-12 20:13:10
JTE-151 is a RORγ inhibitor, which can suppress overactive immune response through inhibition of RORγ related to the activation of Th17 cells, making JTE-151 possible to be used in autoimmune disease research[1].

Name	JTE-151

Description	JTE-151 is a RORγ inhibitor, which can suppress overactive immune response through inhibition of RORγ related to the activation of Th17 cells, making JTE-151 possible to be used in autoimmune disease research[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> ROR Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Hiromu Takiguchi, et al. Practical Synthesis of Chiral 3-(Hydroxyiminomethyl)adipic Acid, a Key Intermediate of the ROR-γ Inhibitor JTE-151, via Crystallization-Induced Dynamic Resolution

Molecular Formula	C₂₈H₃₇ClN₂O₄
Molecular Weight	501.06