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2225902-98-5

2225902-98-5 structure

2225902-98-5 structure

Name: NBI-961
Chemical Name: NBI-961
CAS Number: 2225902-98-5
Molecular Formula: C₂₈H₂₇F₃N₆O₂S
Molecular Weight: 568.61
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2024-03-06 19:15:00
Modify Date: 2024-03-06 19:15:00
NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1].

Name	NBI-961

Description	NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Mason McCrury, et al. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Mol Cancer Ther. 2023 Oct 11.

Molecular Formula	C₂₈H₂₇F₃N₆O₂S
Molecular Weight	568.61

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