1144114-27-1

1144114-27-1 structure

1144114-27-1 structure

Name: POP-3MB
Chemical Name: POP-3MB
CAS Number: 1144114-27-1
Molecular Formula: C₃₈H₃₉NO₄S
Molecular Weight: 605.79
Catalog: Signaling Pathways MAPK/ERK Pathway ERK
Create Date: 2024-02-09 09:12:30
Modify Date: 2024-02-09 09:12:30
POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].

Name	POP-3MB

Description	POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Stem Cell/Wnt >> ERK
Target	IC50: 2.5 μM (ICMT)[1]
References	[1]. Majmudar JD et al. Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization. Bioorg Med Chem. 2012 Jan 1;20(1):283-95.

Molecular Formula	C₃₈H₃₉NO₄S
Molecular Weight	605.79