POP-3MB

Modify Date: 2024-02-09 09:12:30

POP-3MB Structure
POP-3MB structure
 Common Name POP-3MB
CAS Number 1144114-27-1 Molecular Weight 605.79
Density N/A Boiling Point N/A
Molecular Formula C38H39NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of POP-3MB


POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].

 Names

Name POP-3MB

 POP-3MB Biological Activity

Description POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].
Related Catalog
Target

IC50: 2.5 μM (ICMT)[1]

References

[1]. Majmudar JD et al. Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization. Bioorg Med Chem. 2012 Jan 1;20(1):283-95.  

 Chemical & Physical Properties

Molecular Formula C38H39NO4S
Molecular Weight 605.79
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Chemsrc provides POP-3MB(CAS#:1144114-27-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of POP-3MB are included as well.>> amp version: POP-3MB

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