2832199-45-6

2832199-45-6 structure

Name: TLR7 agonist 14
Chemical Name: TLR7 agonist 14
CAS Number: 2832199-45-6
Molecular Formula: C₂₉H₃₆N₆O₃
Molecular Weight: 516.63
Catalog: Signaling Pathways Immunology/Inflammation Toll-like Receptor (TLR)
Create Date: 2024-03-19 19:50:33
Modify Date: 2024-03-19 19:50:33
TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].

Name	TLR7 agonist 14

Description	TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
Target	TLR7:18 nM (IC50)
References	[1]. Emma G DeYoung, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5- c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368.

Molecular Formula	C₂₉H₃₆N₆O₃
Molecular Weight	516.63