TLR7 agonist 14

Modify Date: 2024-03-19 19:50:33

TLR7 agonist 14 structure	Common Name	TLR7 agonist 14
	CAS Number	2832199-45-6	Molecular Weight	516.63
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₉H₃₆N₆O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TLR7 agonist 14

TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].

Name	TLR7 agonist 14

Description	TLR7 agonist 14 (compound 17b) is a highly potent TLR7 agonist with an EC50 of 18 nM. TLR7 agonist 14 potently induces the activation of mouse macrophages and hPBMCs at low-nanomolar concentrations[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR) Research Areas >> Inflammation/Immunology
Target	TLR7:18 nM (IC50)
References	[1]. Emma G DeYoung, et al. Synthesis and Optimization of 1-Substituted Imidazo[4,5- c]quinoline TLR7 Agonists. ACS Med Chem Lett. 2023 Sep 14;14(10):1358-1368.

Molecular Formula	C₂₉H₃₆N₆O₃
Molecular Weight	516.63