749247-06-1
749247-06-1 structure
- Name: HS-PEG4-CH2CH2COOH
- Chemical Name: 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
- CAS Number: 749247-06-1
- Molecular Formula: C11H22O6S
- Molecular Weight: 282.35400
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2016-08-03 23:07:56
- Modify Date: 2024-01-09 16:31:59
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Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoic acid |
|---|---|
| Synonyms | AmbotzPEG1970 |
| Description | Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C11H22O6S |
|---|---|
| Molecular Weight | 282.35400 |
| Exact Mass | 282.11400 |
| PSA | 113.02000 |
| LogP | 0.45730 |
| Hazard Codes | Xi |
|---|