HS-PEG4-CH2CH2COOH

Modify Date: 2024-01-09 16:31:59

HS-PEG4-CH2CH2COOH Structure
HS-PEG4-CH2CH2COOH structure
Common Name HS-PEG4-CH2CH2COOH
CAS Number 749247-06-1 Molecular Weight 282.35400
Density N/A Boiling Point N/A
Molecular Formula C11H22O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS-PEG4-CH2CH2COOH


Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3-[2-[2-[2-(2-sulfanylethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
Synonym More Synonyms

 HS-PEG4-CH2CH2COOH Biological Activity

Description Thiol-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H22O6S
Molecular Weight 282.35400
Exact Mass 282.11400
PSA 113.02000
LogP 0.45730

 Safety Information

Hazard Codes Xi

 Synonyms

AmbotzPEG1970
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