Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Fmoc-NH-PEG4-CH2COOH
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Fmoc-NH-PEG4-CH2COOH
Price: ￥1748.0/1g
Purity: 97.0%
Stocking Period: 2 Day
Contact: Liu jia

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Fmoc-NH-PEG4-CH2COOH
Price: ￥Inquiry/10g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang

DC Chemicals Limited
China
Product Name: Fmoc-NH-PEG4-CH2COOH
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Fmoc-NH-PEG4-CH2COOH
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

437655-95-3

437655-95-3 structure

Name: Fmoc-NH-PEG4-CH2COOH
Chemical Name: 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18 -oic acid
CAS Number: 437655-95-3
Molecular Formula: C₂₅H₃₁NO₈
Molecular Weight: 473.51600
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-08-31 11:49:54
Modify Date: 2024-01-06 18:14:17
Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18 -oic acid
Synonyms	14-methylpentadecyl bromide 14-morpholin-4-yl-daunomycin 14-Morpholino-daunomycin 14-methyl-1-bromopentadecane Pentadecane,1-bromo-14-methyl

Description	Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Maggie Lu, et al. Linker-wirkstoff und antikörper-wirkstoff-konjugat (adc) damit. EP3335734A1.

Molecular Formula	C₂₅H₃₁NO₈
Molecular Weight	473.51600
Exact Mass	473.20500
PSA	116.04000
LogP	2.88050
Storage condition	2-8°C

894427-95-3

~65%

437655-95-3

Literature: N.V. ORGANON Patent: WO2007/42469 A2, 2007 ; Location in patent: Page/Page column 15; 16 ;

195071-49-9

28920-43-6

~63%

437655-95-3

Literature: Bogdan, Niculina D.; Matache, Mihaela; Meier, Veronika M.; Dobrotae, Cristian; Dumitru, Ioana; Roiban, Gheorghe D.; Funeriu, Daniel P. Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2170 - 2180

112-60-7

437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

77544-60-6

437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

86770-74-3

437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

86770-67-4

437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

106984-09-2

437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

Precursor 7
195071-49-9 28920-43-6 112-60-7 77544-60-6
86770-74-3 86770-67-4 106984-09-2
DownStream 0

437655-95-3	557756-85-1
868594-41-6	876345-13-0
2629308-66-1	2291257-76-4
635287-26-2	260367-12-2
675606-79-8	868594-52-9
1158522-08-7	940364-43-2
134104-43-1	131615-57-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4
849349-65-1	127437-46-1