Fmoc-NH-PEG4-CH2COOH

Modify Date: 2024-01-06 18:14:17

Fmoc-NH-PEG4-CH2COOH structure	Common Name	Fmoc-NH-PEG4-CH2COOH
	CAS Number	437655-95-3	Molecular Weight	473.51600
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₃₁NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Fmoc-NH-PEG4-CH2COOH

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18 -oic acid
Synonym	More Synonyms

Description	Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Maggie Lu, et al. Linker-wirkstoff und antikörper-wirkstoff-konjugat (adc) damit. EP3335734A1.

Molecular Formula	C₂₅H₃₁NO₈
Molecular Weight	473.51600
Exact Mass	473.20500
PSA	116.04000
LogP	2.88050
Storage condition	2-8°C

FmocNH-PEG4-t-b...

CAS#:894427-95-3

~65%

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: N.V. ORGANON Patent: WO2007/42469 A2, 2007 ; Location in patent: Page/Page column 15; 16 ;

Amino-PEG4-CH2COOH

CAS#:195071-49-9

9-Fluorenylmeth...

CAS#:28920-43-6

~63%

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Bogdan, Niculina D.; Matache, Mihaela; Meier, Veronika M.; Dobrotae, Cristian; Dumitru, Ioana; Roiban, Gheorghe D.; Funeriu, Daniel P. Chemistry - A European Journal, 2010 , vol. 16, # 7 p. 2170 - 2180

2,2'-((Oxybis(e...

CAS#:112-60-7

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

Tetraethylene g...

CAS#:77544-60-6

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

Amino-PEG4-alcohol

CAS#:86770-74-3

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

Azido-PEG4-alcohol

CAS#:86770-67-4

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

N-Boc-PEG4-alcohol

CAS#:106984-09-2

Fmoc-NH-PEG4-CH2COOH

CAS#:437655-95-3

Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48

Precursor 7
CAS#:195071-49-9 Amino-PEG4-CH2COOH CAS#:28920-43-6 9-Fluorenylmeth... CAS#:112-60-7 2,2'-((Oxybis(e... CAS#:77544-60-6 Tetraethylene g...
CAS#:86770-74-3 Amino-PEG4-alcohol CAS#:86770-67-4 Azido-PEG4-alcohol CAS#:106984-09-2 N-Boc-PEG4-alcohol
DownStream 0

14-methylpentadecyl bromide

14-morpholin-4-yl-daunomycin

14-Morpholino-daunomycin

14-methyl-1-bromopentadecane

Pentadecane,1-bromo-14-methyl

Fmoc-NH-PEG4-CH2COOH

Use of Fmoc-NH-PEG4-CH2COOH

Names

Fmoc-NH-PEG4-CH2COOH Biological Activity

Chemical & Physical Properties

Synthetic Route

Precursor & DownStream

Synonyms