145739-56-6
145739-56-6 structure
- Name: Tetomilast
- Chemical Name: 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid
- CAS Number: 145739-56-6
- Molecular Formula: C19H18N2O4S
- Molecular Weight: 369.434
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2018-12-26 09:22:49
- Modify Date: 2025-09-14 19:40:13
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Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the treatment of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD).
| Name | 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid |
|---|---|
| Synonyms |
Tetomilast
2-Pyridinecarboxylic acid, 6-[5-(3,4-diethoxyphenyl)-3-thienyl]- UNII-S6RXB5KF56 6-[5-(3,4-Diethoxyphenyl)-3-thienyl]-2-pyridinecarboxylic acid 6-[2-(3,4-diethoxypheny)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid |
| Description | Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the treatment of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD). |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 526.1±50.0 °C at 760 mmHg |
| Molecular Formula | C19H18N2O4S |
| Molecular Weight | 369.434 |
| Flash Point | 272.0±30.1 °C |
| Exact Mass | 369.103485 |
| PSA | 109.78000 |
| LogP | 4.39 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.601 |
| HS Code | 2934100090 |
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| Precursor 5 | |
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| DownStream 0 | |
| HS Code | 2934100090 |
|---|---|
| Summary | 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |