Henan Tianfu Chemical Co., Ltd.
China
Product Name: High purity CAS 21442-01-3 N-(2-HYDROXYPROPYL)METHACRYLAMIDE in stock
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
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21442-01-3

21442-01-3 structure

Name: N-(2-HYDROXYPROPYL)METHACRYLAMIDE
Chemical Name: n-(2-hydroxypropyl)methacrylamide
CAS Number: 21442-01-3
Molecular Formula: C₇H₁₃NO₂
Molecular Weight: 143.18400
Catalog: Research Areas Infection
Create Date: 2018-09-06 11:31:19
Modify Date: 2024-01-05 12:15:51
N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1].

Name	n-(2-hydroxypropyl)methacrylamide
Synonyms	1-methacryloylamino-2-hydroxypropane

Description	N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
In Vivo	At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition)[1].
References	[1]. Nan A, et al. N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. J Control Release. 2001 Dec 13;77(3):233-43. [2]. Hao Tang, et al. Comb-like Poly(N-(2-hydroxypropyl) methacrylamide) Doxorubicin Conjugates: The Influence of Polymer Architecture and Composition on the Biological Properties. Chinese Journal of Polymer Science volume 36, pages1225-1238(2018).

Risk Phrases	36/37/38
Safety Phrases	26-36/37/39
RIDADR	NONH for all modes of transport
HS Code	2924199090

78-96-6

920-46-7

~70%

21442-01-3

897017-30-0

21442-01-3

Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498

675589-71-6

21442-01-3

Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498

760-93-0

78-96-6

~42%

21442-01-3

Literature: Solovskii; Denisov; Ryadinskaya; Petukhova; Okulova Russian Journal of Applied Chemistry, 1999 , vol. 72, # 8 p. 1443 - 1449

675589-71-6

21442-01-3

923-17-1

Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498

897017-30-0

79-33-4

21442-01-3

Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498

HS Code	2924199090
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%