N-(2-HYDROXYPROPYL)METHACRYLAMIDE
N-(2-HYDROXYPROPYL)METHACRYLAMIDE structure
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Common Name | N-(2-HYDROXYPROPYL)METHACRYLAMIDE | ||
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| CAS Number | 21442-01-3 | Molecular Weight | 143.18400 | |
| Density | 1.002g/cm3 | Boiling Point | 321.2ºC at 760mmHg | |
| Molecular Formula | C7H13NO2 | Melting Point | 70 °C | |
| MSDS | Chinese USA | Flash Point | 148.1ºC | |
Use of N-(2-HYDROXYPROPYL)METHACRYLAMIDEN-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1]. |
| Name | n-(2-hydroxypropyl)methacrylamide |
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| Synonym | More Synonyms |
| Description | N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1]. |
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| Related Catalog | |
| In Vivo | At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition)[1]. |
| References |
| Density | 1.002g/cm3 |
|---|---|
| Boiling Point | 321.2ºC at 760mmHg |
| Melting Point | 70 °C |
| Molecular Formula | C7H13NO2 |
| Molecular Weight | 143.18400 |
| Flash Point | 148.1ºC |
| Exact Mass | 143.09500 |
| PSA | 49.33000 |
| LogP | 0.45040 |
| Vapour Pressure | 2.43E-05mmHg at 25°C |
| Index of Refraction | 1.46 |
| Risk Phrases | 36/37/38 |
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| Safety Phrases | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
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~70%
N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Ebbesen, Morten F.; Schaffert, David H.; Crowley, Michael L.; Oupicky, David; Howard, Kenneth A. Journal of Polymer Science, Part A: Polymer Chemistry, 2013 , vol. 51, # 23 p. 5091 - 5099 |
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N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
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~%
N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
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~42%
N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Solovskii; Denisov; Ryadinskaya; Petukhova; Okulova Russian Journal of Applied Chemistry, 1999 , vol. 72, # 8 p. 1443 - 1449 |
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~%
N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
|
~%
N-(2-HYDROXYPRO... CAS#:21442-01-3 |
| Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging
Biomaterials 35(22) , 5760-70, (2014) N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, ... |
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Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids.
Biomater. Sci. 3 , 1085-95, (2015) Many attempts have been made in the application of multicellular tumor spheroids (MCTS) as a 3D tumor model to investigate their biological responses upon introduction of polymeric micelles as nanocar... |
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Vesicular glutamate transporter expression level affects synaptic vesicle release probability at hippocampal synapses in culture.
J. Neurosci. 34(35) , 11781-91, (2014) The vesicular glutamate transporter (VGLUT) plays an essential role in synaptic transmission by filling vesicles with glutamate. At mammalian synapses, VGLUT expression level determines the amount of ... |
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