N-(2-HYDROXYPROPYL)METHACRYLAMIDE structure
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Common Name | N-(2-HYDROXYPROPYL)METHACRYLAMIDE | ||
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CAS Number | 21442-01-3 | Molecular Weight | 143.18400 | |
Density | 1.002g/cm3 | Boiling Point | 321.2ºC at 760mmHg | |
Molecular Formula | C7H13NO2 | Melting Point | 70 °C | |
MSDS | Chinese USA | Flash Point | 148.1ºC |
Use of N-(2-HYDROXYPROPYL)METHACRYLAMIDEN-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1]. |
Name | n-(2-hydroxypropyl)methacrylamide |
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Synonym | More Synonyms |
Description | N-(2-Hydroxypropyl)methacrylamide is used to synthesize copolymers for the targeted delivery of antileishmanial agents in Visceral leishmaniasis (VL) [1][1]. |
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Related Catalog | |
In Vivo | At 5 mg/kg body weight drug equivalent dose, all N-(2-Hydroxypropyl)methacrylamide copolymer-drug conjugates which contained lysosomally degradable side chains shows significant in vivo antileishmanial activity (>99% inhibition)[1]. |
References |
Density | 1.002g/cm3 |
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Boiling Point | 321.2ºC at 760mmHg |
Melting Point | 70 °C |
Molecular Formula | C7H13NO2 |
Molecular Weight | 143.18400 |
Flash Point | 148.1ºC |
Exact Mass | 143.09500 |
PSA | 49.33000 |
LogP | 0.45040 |
Vapour Pressure | 2.43E-05mmHg at 25°C |
Index of Refraction | 1.46 |
Risk Phrases | 36/37/38 |
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Safety Phrases | 26-36/37/39 |
RIDADR | NONH for all modes of transport |
HS Code | 2924199090 |
~70% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Ebbesen, Morten F.; Schaffert, David H.; Crowley, Michael L.; Oupicky, David; Howard, Kenneth A. Journal of Polymer Science, Part A: Polymer Chemistry, 2013 , vol. 51, # 23 p. 5091 - 5099 |
~% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
~% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
~42% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Solovskii; Denisov; Ryadinskaya; Petukhova; Okulova Russian Journal of Applied Chemistry, 1999 , vol. 72, # 8 p. 1443 - 1449 |
~% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
~% N-(2-HYDROXYPRO... CAS#:21442-01-3 |
Literature: Macromolecules, , vol. 36, # 20 p. 7491 - 7498 |
HS Code | 2924199090 |
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Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
The influence of linker length on the properties of cathepsin S cleavable177Lu-labeled HPMA copolymers for pancreatic cancer imaging
Biomaterials 35(22) , 5760-70, (2014) N-(2-hydroxypropyl)-methacrylamide (HPMA) copolymers have shown promise for application in the detection and staging of cancer. However, non-target accumulation, particularly in the liver and spleen, ... |
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Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids.
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1-methacryloylamino-2-hydroxypropane |