50586-80-6

50586-80-6 structure

Name: m-PEG2-Tos
Chemical Name: 2-(2-methoxyethoxy)ethanol,4-methylbenzenesulfonic acid
CAS Number: 50586-80-6
Molecular Formula: C₁₂H₁₈O₅S
Molecular Weight: 292.34900
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2016-01-12 23:26:31
Modify Date: 2025-08-24 21:27:55
m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name	2-(2-methoxyethoxy)ethanol,4-methylbenzenesulfonic acid
Synonyms	diethylene glycol monomethyl ether-p-toluene sulfonate diethyleneglycol monomethyl ether tosylate

Description	m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

111-77-3

98-59-9

~99%

50586-80-6

Literature: Harjani, Jitendra R.; Liang, Chen; Jessop, Philip G. Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1683 - 1691

112-35-6

98-59-9

~10%

50586-80-6

71776-35-7

98-59-9

50586-80-6

Literature: Chao,Y. et al. Journal of the American Chemical Society, 1979 , vol. 101, # 17 p. 4948 - 4958