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Shanghai Jizhi Biochemical Technology Co., Ltd
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ShangHai DC Chemicals Co.,Ltd
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DC Chemicals Limited
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Dayang Chem (Hangzhou) Co., Ltd.
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Product Name: Triethylene glycol monomethyl ether suppliers in China
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112-35-6

112-35-6 structure

Name: m-PEG3-OH
Chemical Name: triethylene glycol monomethyl ether
CAS Number: 112-35-6
Molecular Formula: C₇H₁₆O₄
Molecular Weight: 164.199
Catalog: Catalysts and additives polymer
Create Date: 2018-02-26 08:00:00
Modify Date: 2024-01-02 10:25:37
m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name	triethylene glycol monomethyl ether
Synonyms	UNII-DN0P4Q4I16 Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)- Triethylene glycol monomethyl ether 3,6,9-Trioxa-1-decanol Triglycol monomethyl ether 2-(2-(2-Methoxyethoxy)ethoxy)ethanol Methoxytriglycol triethylene glycol methyl ether Methoxytriethylene glycol 2-[2-(2-Methoxyethoxy)ethoxy]ethanol Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]- Methyltrioxitol Methyl Triglycol Methyltriglycol MFCD00002875 Methyl triethylene glycol EINECS 203-962-1

Description	m-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Density	1.0±0.1 g/cm3
Boiling Point	233.9±20.0 °C at 760 mmHg
Melting Point	-44ºC
Molecular Formula	C₇H₁₆O₄
Molecular Weight	164.199
Flash Point	95.3±21.8 °C
Exact Mass	164.104858
PSA	47.92000
LogP	-1.51
Vapour density	5.66 (vs air)
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.427

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KL6390000

CHEMICAL NAME :: Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-

CAS REGISTRY NUMBER :: 112-35-6

BEILSTEIN REFERENCE NO. :: 1700198

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C7-H16-O4

MOLECULAR WEIGHT :: 164.23

WISWESSER LINE NOTATION :: Q2O2O2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11300 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 7100 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0892 No. of Facilities: 13261 (estimated) No. of Industries: 85 No. of Occupations: 32 No. of Employees: 80404 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0892 No. of Facilities: 2416 (estimated) No. of Industries: 22 No. of Occupations: 29 No. of Employees: 18956 (estimated) No. of Female Employees: 9842 (estimated)

Personal Protective Equipment	Eyeshields;Gloves
Hazard Codes	Xi
Safety Phrases	S24/25-S22
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	KL6390000
HS Code	2909499000

Precursor 10
620-24-6 249508-40-5 77-78-1 112-27-6
16024-58-1 75-21-8 67-56-1 55489-58-2
74-88-4 81194-71-0
DownStream 10
146395-16-6 184709-01-1 19685-21-3 18854-48-3
1297518-94-5 2387-23-7 250608-58-3 26256-87-1
24493-59-2 25990-94-7

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

112-35-6	2173095-09-3
356066-46-1	67319-28-2
74654-05-0	74654-06-1
16024-60-5	2055040-96-3
153364-63-7	857284-78-7
1351582-31-4	1351610-43-9
1158522-08-7	1260650-33-6
940364-43-2	130892-41-0
1246665-54-2	134104-43-1
131615-57-1	6906-52-1