57576-41-7

57576-41-7 structure

Name: Norcepharadione B
Chemical Name: Norcepharadione B
CAS Number: 57576-41-7
Molecular Formula: C₁₈H₁₃NO₄
Molecular Weight: 307.30
Catalog: Natural product Alkaloid
Create Date: 2017-04-24 10:51:06
Modify Date: 2024-01-03 12:55:53
Norcepharadione B is an alkaloid that can be isolated from Houttuynia cordata. Norcepharadione B exhibits moderate cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cell line with ED50s of 40, 26.4, 40, 14.2 and 38.2 μg/mL, respectively[1].

Name	Norcepharadione B
Synonyms	1,2-Dimethoxy-4H-dibenzo[de,g]quinoline-4,5(6H)-dione norcepharadione 4H-Dibenzo[de,g]quinoline-4,5(6H)-dione, 1,2-dimethoxy-

Description	Norcepharadione B is an alkaloid that can be isolated from Houttuynia cordata. Norcepharadione B exhibits moderate cytotoxicity against A-549, SK-OV-3, SK-MEL-2, XF-498 and HCT-15 cell line with ED50s of 40, 26.4, 40, 14.2 and 38.2 μg/mL, respectively[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kim, S.-K., et al. Cytotoxic alkaloids fromHouttuynia cordate. Archives of Pharmacal Research, 24(6), 518–521.

Hazard Codes	Xi

82359-80-6

118-92-3

~63%

57576-41-7

Literature: Atanes, N.; Castedo, L.; Guitian, E.; Saa, C.; Saa, J. M.; Suau, R. Journal of Organic Chemistry, 1991 , vol. 56, # 9 p. 2984 - 2988

82359-79-3

118-92-3

57576-41-7

Literature: Castedo, Luis; Guitian, Enrique; Saa, Jose M.; Suau, Rafael Tetrahedron Letters, 1982 , vol. 23, # 4 p. 457 - 458