62124-69-0
62124-69-0 structure
- Name: Methyl-PEG4-acyl chloride
- Chemical Name: 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl carbonochloridate
- CAS Number: 62124-69-0
- Molecular Formula: C10H19ClO6
- Molecular Weight: 270.70700
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2017-02-09 08:47:09
- Modify Date: 2024-01-10 23:27:32
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Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl carbonochloridate |
|---|---|
| Synonyms |
tetraethylene glycol monomethyl ether chloroformate
Carbonochloridic acid,3,6,9,12-tetraoxatridec-1-yl ester 2-{2-[2-(2-methoxyethoxy)-ethoxy]ethoxy}ethyl chloroformate Methyl-PEG4-acyl chloride |
| Description | Methyl-PEG4-acyl chloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C10H19ClO6 |
|---|---|
| Molecular Weight | 270.70700 |
| Exact Mass | 270.08700 |
| PSA | 63.22000 |
| LogP | 1.05800 |
