CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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EM4740000
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CHEMICAL NAME :
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1-Butene, 3,4-dichloro-
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CAS REGISTRY NUMBER :
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760-23-6
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BEILSTEIN REFERENCE NO. :
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1739135
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LAST UPDATED :
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199710
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DATA ITEMS CITED :
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7
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MOLECULAR FORMULA :
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C4-H6-Cl2
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MOLECULAR WEIGHT :
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125.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LC50 - Lethal concentration, 50 percent kill
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2100 ppm/4H
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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724 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Behavioral - excitement Lungs, Thorax, or Respiration - dyspnea
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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75 ug/kg
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SEX/DURATION :
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male 75 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
MUTATION DATA
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TEST SYSTEM :
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Rodent - rat
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DOSE/DURATION :
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13700 ug/m3/30D (Intermittent)
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REFERENCE :
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ZKMAAX Zhurnal Eksperimental'noi i Klinicheskoi Meditsiny. Journal of Experimental and Clinical Medicine. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1962- Volume(issue)/page/year: 25,335,1985
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