79049-30-2

79049-30-2 structure

Name: N-Desethyl amodiaquine dihydrochloride
Chemical Name: 4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol,dihydrochloride
CAS Number: 79049-30-2
Molecular Formula: C₁₈H₂₀Cl₃N₃O
Molecular Weight: 400.73
Catalog: Signaling Pathways Anti-infection Parasite
Create Date: 2017-06-18 06:17:21
Modify Date: 2024-01-09 11:47:25
N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].

Name	4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol,dihydrochloride
Synonyms	Desethylamodiaquine hydrochloride

Description	N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
References	[1]. Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199(11):1575-82.

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution
Flash Point(F)	48.2 °F
Flash Point(C)	9 °C