N-Desethyl amodiaquine dihydrochloride structure
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Common Name | N-Desethyl amodiaquine dihydrochloride | ||
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CAS Number | 79049-30-2 | Molecular Weight | 400.73 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C18H20Cl3N3O | Melting Point | N/A | |
MSDS | N/A | Flash Point | 48.2 °F | |
Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger |
Use of N-Desethyl amodiaquine dihydrochlorideN-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1]. |
Name | 4-[(7-chloroquinolin-4-yl)amino]-2-(ethylaminomethyl)phenol,dihydrochloride |
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Synonym | More Synonyms |
Description | N-Desethyl amodiaquine dihydrochloride is the major biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent. IC50 values for strains V1/S and 3D7 are 97 nM and 25 nM, respectively[1]. |
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Related Catalog | |
References |
Molecular Formula | C18H20Cl3N3O |
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Molecular Weight | 400.73 |
Exact Mass | 399.06700 |
PSA | 57.18000 |
LogP | 6.51480 |
Symbol |
GHS02, GHS06, GHS08 |
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Signal Word | Danger |
Hazard Statements | H225-H301 + H311 + H331-H370 |
Precautionary Statements | P210-P260-P280-P301 + P310-P311 |
RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
Flash Point(F) | 48.2 °F |
Flash Point(C) | 9 °C |
In vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, quinine, mefloquine and halofantrine in Abidjan (Côte d'Ivoire).
Afr. Health Sci. 10(2) , 111-6, (2010) Malaria is the primary cause of hospitalization in Côte d'Ivoire. Early treatment is one of the strategies to control this illness. However, the spread of resistance of Plasmodium falciparum to antima... |
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Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue.
Proc. Natl. Acad. Sci. U. S. A. 108(47) , E1214-23, (2011) Clinical studies and mathematical models predict that, to achieve malaria elimination, combination therapies will need to incorporate drugs that block the transmission of Plasmodium falciparum sexual ... |
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In vitro assessment of drug resistance in Plasmodium falciparum in five States of India.
Indian J. Med. Res. 135(4) , 494-9, (2012) In vitro assays are an important tool to assess baseline sensitivity and monitor the drug response of Plasmodium falciparum over time and place and, therefore, can provide background information for t... |
Desethylamodiaquine hydrochloride |