Top Suppliers:I want be here



120-82-1

120-82-1 structure
120-82-1 structure

Name 1,2,4-trichlorobenzene
Synonyms 1,2,5-Trichlorobenzene
EINECS 204-428-0
1,4,5-trichlorobenzene
1,2,4-Trichlorbenzene
Benzene, 1,2,4-trichloro-
MFCD00000547
1,2,4-trichloro-benzene
Trojchlorobenzen
1,2,4-Trichlorobenzene
Hostetex l-pec
1,2,4-Trichlorbenzol
as-trichlorobenzene
1,2,4-Trichlorobenze
1,2,4-Trichlorobenzol
1,3,4-trichlorobenzene
1,2,4-trichlorobenzene—
Hipochem GM
Density 1.4±0.1 g/cm3
Boiling Point 211.4±20.0 °C at 760 mmHg
Melting Point 16 °C(lit.)
Molecular Formula C6H3Cl3
Molecular Weight 181.447
Flash Point 126.7±0.0 °C
Exact Mass 179.930038
LogP 3.82
Vapour density >6 (vs air)
Vapour Pressure 0.3±0.4 mmHg at 25°C
Index of Refraction 1.567
Stability Stable. Incompatible with strong oxidizing agents. Combustible.
Water Solubility INSOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DC2100000
CHEMICAL NAME :
Benzene, 1,2,4-trichloro-
CAS REGISTRY NUMBER :
120-82-1
BEILSTEIN REFERENCE NO. :
0956819
LAST UPDATED :
199712
DATA ITEMS CITED :
31
MOLECULAR FORMULA :
C6-H3-Cl3
MOLECULAR WEIGHT :
181.44
WISWESSER LINE NOTATION :
GR BG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
756 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6139 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1223 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
280 mg/kg/14D-C
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
7380 mg/kg/13W-C
TOXIC EFFECTS :
Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
1800 mg/kg
SEX/DURATION :
female 9-13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
750 mg/kg
SEX/DURATION :
female 3 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 2,111,1987 *** REVIEWS *** ACGIH TLV-CL 37 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-BELGIUM:STEL 5 ppm (37 mg/m3) JAN 1993 OEL-DENMARK:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-FINLAND:TWA 5 ppm (40 mg/m3);STEL 10 ppm (74 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-GERMANY:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (40 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (40 mg/m3);STEL 5 ppm (40 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 1,2,4-TRICHLOROBENZENE-air:CL 5 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83334 No. of Facilities: 74 (estimated) No. of Industries: 4 No. of Occupations: 8 No. of Employees: 1687 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83334 No. of Facilities: 78 (estimated) No. of Industries: 6 No. of Occupations: 14 No. of Employees: 4033 (estimated) No. of Female Employees: 1463 (estimated)
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H315-H410
Precautionary Statements P273-P501
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful
Risk Phrases R22;R38;R50/53
Safety Phrases S23-S37/39-S60-S61-S45-S36/37-S16
RIDADR UN 2321 6.1/PG 3
WGK Germany 3
RTECS DC2100000
Packaging Group III
Hazard Class 6.1
HS Code 29036990
HS Code 2903999090
Summary 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%